- Политикa конфиденциальности
The Imperial College of London, which is not only a college, but also a scientific base for many scientists, made a big discovery. Rather, the scientists who work there. They found a protein that activates the T cells of the immune system, which can resist cancers.
The genomes of mice, mutations in them were studied, as a result of which the protein level increased, which in turn activated T cells, forming antitumor immunity in those same mice.
Scientists agreed that this protein is a kind of generator that allows you to activate or, conversely, slow down the activity of T cells of the immune system. In addition, in addition to the fact that T cells successfully fight cancers, the excreted protein gives the ability to remember and recognize tumor cells and viruses, and its memory increases.
Many experts believe that they have found a fundamentally new method of combating cancer.
You can talk about such a topic as cancer treatment abroad for a long time. Let’s look at specific examples.
Traditional methods for diagnosing cancer can sink into oblivion. The recently created “liquid biopsy” can permanently change people’s perception of existing diagnostic methods. The fact is that this same “liquid biopsy” is able to make cancer cells glow in the dark.
Americans have developed a method for attaching fluorescent “tags” to cancer cell proteins. Special rays make it possible to illuminate the tumor. Trial studies were conducted, and this method has proven itself in working with patients with cancer of the breast, pancreas and prostate. Theoretically, the main advantage is that such a “backlight” makes it possible to observe in real time the location, size of tumors, which will undoubtedly benefit in choosing the right treatment method.
Scientists also believe that real-time monitoring of the development of cancers will significantly accelerate and facilitate the treatment process itself. For example, after a course of chemotherapy, only after a few weeks, the doctor can tell from the analysis whether the patient responds to these drugs or not, the tumor has decreased, or is it all in vain? “Liquid biopsy” provides an opportunity to get an answer to this question almost immediately.
What is still very important, this technique allows scientists to understand the principle of the spread of metastases in the body. The composition of the “liquid biopsy” includes stains with antibodies that attach to the proteins of cancer cells. After this substance combines with the protein of the affected cell, it will change color, allowing doctors to determine its location.
The human protein encoded by the GCCR gene is a glucocorticoid receptor. In the metabolism, cell activity and immune response, this receptor plays an important role, it is present throughout the body. Many groups of drugs act directly through it.
A research team from Michigan states that after a series of studies, there is evidence of a new role for the glucocorticoid receptor regarding the development of cancerous tumors.
As you know, chromosomal failure is a characteristic sign of cancer. As a result of the studies, it was found that in cells that did not have the GCCR gene, which is responsible for encoding the receptor, cell division in chromosome formation often occurs, in other words, malfunctions. Also in the future, scientists found that the number of glucocorticoid receptors in cancer cells is too low compared to healthy cells.
Professor David Ray of the Institute for Human Development at the University of Manchester says that the cause of cancer cells lies in the wrong division of themselves. It is worth saying that until that time, scientists did not study the role of the glucocorticoid receptor in this process.
To find confirmation of his hypothesis, analyzes of malignant cells of the colon, liver, lungs and mammary gland were performed. It has been proven that a low receptor level is a common feature for various types of cancers.
Scientists intend to continue their research in search of new possible methods of combating cancer pathology.
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